Publications

Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis. Delgado-Olguín P, Huang Y, Li X, Christodoulou D, Seidman CE, Seidman JG, Tarakhovsky A, Bruneau BG.
Gladstone Institute of Cardiovascular Disease, San Francisco, California, USA.
Nat Genet. 2012 Jan 22. doi: 10.1038/ng.1068. [Epub ahead of print].

PRC2 directly methylates GATA4 and represses its transcriptional activity. He A, Shen X, Ma Q, Cao J, von G, A., Zhou P, Wang G, Marquez VE, Orkin SH, Pu WT.
Genes & Development. 2012;26:37-42.

Heart Polycomb Repressive Complex 2 Regulates Normal Development of the Mouse. Aibin He, Qing Ma, Jingjing Cao, Alexander von Gise, Pingzhu Zhou, Huafeng Xie, Bing Zhang, Michael Hsing, Danos Christodoulou, Patrick Cahan, George Q. Daley, Sek Won Kong, Stuart H. Orkin, Christine E. Seidman, J.G. Seidman and William T. Pu.
Circulation Research published online December 8, 2011. Data Supplement (unedited) at: http://circres.ahajournals.org/content/suppl/2011/12/08/CIRCRESAHA.111.252205.DC1.html

Repairing the Littlest Hearts: Armed with a major new grant and led by Dr. Bruce Gelb, Mount Sinai researchers are tackling the causes of heart disease in children. 2010.

Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart. A. He, S.W. Kong, Q. Ma, W.T. Pu.  Proc Natl Acad Sci U S A. 2011;108:5632-5637.

CompleteMOTIFs: DNA Motif discovery platform for transcription factor binding experiments. L Kuttippurathu, Bioinformatics (2011) 27(5): 715-717.

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